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The Food Biomarker Alliance

JPI HDHL JFA “Biomarkers for Nutrition and Health” (BioNH 2014)
The Food Biomarker Alliance
Edith Feskens
Wageningen University
The Netherlands


Partner Organization Partner Country
University College DublinIreland
University of OsloNorway
Department of Nutrition, Exercise and SportsDenmark
RIVMThe Netherlands
Ghent UniversityBelgium
University of AlbertaCanada
National Food InstituteDenmark
Technische Universität MünchenGermany
Fondazione Edmund MachItaly
Università di BolognaItaly
University Medical Center GroningenThe Netherlands
NUTRIM Nutrition and Toxicology Research Institute MaastrichtThe Netherlands
University of BarcelonaSpain
Max Rubner-InstituteGermany
Centre Hospitalier Universitaire Vaudois (CHUV)Switzerland
Helmholtz Zentrum MünchenGermany
TNOThe Netherlands

1. Overall project description

1.1 Summary

Food questionnaires and/or food diaries are commonly used to measure dietary intake in population based studies. Biomarkers, however, may provide more reliable intake measures than self-reported data. Unfortunately, only very few food biomarkers have been sufficiently validated.

In December 2014, the JPI HDHL Food Biomarkers Alliance (FOODBALL) project commenced, which aims to develop strategies for the discovery and validation of biomarker for foods that are commonly consumed in Europe. For this purpose, FOODBALL is a collaboration between 22 partners from 11 countries, including Belgium, Canada, Denmark, France, Germany, Ireland, Italy, Norway, Spain, Switzerland, and the Netherlands.

FoodBall systematically explored and/or validated a range of dietary biomarkers covering important and public health relevant foods in Europe, where metabolomics techniques were used for the discovery of biomarkers as main –omics technique. Common biomarker sampling techniques (i.e. venous/arterial blood collection) and promising new biomarker sampling techniques (i.e. dried blood spot (DBS) analysis) were studied as well. Subsequently, these newly-developed approaches were tested in studies where associations between nutrient and health status were examined. In addition, to aid the harmonisation of methodologies, FoodBall developed new and advanced existing platforms for sharing knowledge and resources with the scienctific community (i.e. open-access databases on food metabolites, software tools for annotation of food metabolites, and chemical libraries).

More information can be found on the project website: http://foodmetabolome.org/

1.2 Highlights

4. Impact

4.1 List of publications

AuthorsTitleYear, Issue, PPPartners NumberDoiPdf

4.2 Presentation of the project

Target groupAuthorsMeans of communicationHyperlinkPdf

4.3 List of submitted patents and other outputs

Patent licencePartners involvedYearInternational eu or national patentCommentPdf

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This project has received funding from the European Union’s
H2020 Research and Innovation Programme under grant agreement n.696300

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