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- The aim of the project is to develop a comprehensive toolbox of optimized existing and novel technologies for developing healthy, high quality, safe and sustainable fish products from pelagic fish species. Pelagic fish is rich in omega-3 lipids (EPA and DHA) with documented beneficial health effects, easily digestible proteins; vitamins (E and D). However, during processing; high temperatures…
- The LONGLIFE project involves Irish research partners (Teagasc and UCC) to develop innovative processes for transforming food substrates (milk, Teagasc and cereals, UCC) into fermentates, using novel strains of lactic acid bacteria (LAB) and yeasts to produce value-added fermented liquids and powders, and long-fermented sourdough bread with improved health benefits, improved organoleptic qualities…
- An increased intestinal permeability (IP), also known as leaky gut, could be responsible for activation of the immune system and inflammation, a common mechanism in many chronic age-related diseases. The MaPLE project tested the hypothesis that an increased intake of polyphenol-rich foods can reduce IP and the quantity of inflammogenic bacterial factors in the bloodstream, promoting a protective…
- Background and aimThe human gut microbiota is a complex ecosystem consisting of hundreds to thousands of distinct bacterial species which provide important immune, metabolic and trophic functions for their host. Our knowledge on the processes contributing to microbial dysbiosis has a direct impact on our ability to manage and maintain human health. Early childhood appears a crucial age-window…
- BackgroundBacteria play a crucial role in our healthy development, and in protecting against chronic disease. The goal of EarlyVir was to find out whether the same applies for viruses and if we can isolate important viruses and use them as a technology to improve human health.Objectives:Determine the viral composition of the infant gut at age 1 yearDetermine whether it was influenced by the diet…
- Microbial colonization of the new-born is essential for the development of the physiological homeostasis of the host. Perturbations of early-life colonization may have long-lasting effects on host health; specific alterations seem to precede the development of disease, including both communicable and non-communicable diseases. Thus, early microbiota establishment has a profound effect on long-term…
- The DINAMIC project investigates the interplay between diet, the gut microbiota, and the host in the context of cardiometabolic health. Using state-of-the-art prospective human cohorts, microbiota profiling allows the consortium to identify specific features associated with disease states. Clinical trials based on dietary interventions and fecal microbiota transplantation were designed and are…
- Background and aimThe aryl hydrocarbon receptor (AhR) is a transcription factor recently shown to be crucial for the maintenance of intestinal homeostasis, however its precise gut luminal activators and functional consequences are unknown. Activators originate from (i) the diet, such as indole-3-carbinol from cruciferous vegetables, (ii) the microbiota, (iii) lactic acid bacteria, used in food or…
- Within MaNuEL, 22 research groups from 7 countries with complementary expertise in the field of malnutrition in older persons are now actively collaborating, supported by an advisory board of 6 renowned experts in the field of geriatric nutrition, some representing relevant European organisations. The collaboration started with a kick-off meeting in April 2016 in Nurnberg, and is supported by a…
- Obesity is a problem that represents a significant health and economic burden in Europe and throughout the world. The prevalence of obesity across European countries has tripled in the last several decades, making it one of the leading public health challenges.A critical part of addressing this global epidemic is to improve the evidence base for more effective treatments for obesity; however, a…
- Background and aimThe VALID project aims to validate plasma valerolactones as stable biomarkers of catechin- and procyanidin- rich foods and to demonstrate their association with markers of metabolic health, inflammation and cognitive function in an older European population, building upon the existing TUDA study of 5,186 older adults. The VALID project has 5 objectives, to evaluate:Plasma PVLs…
- Background and aimRecent findings convincingly demonstrate that Advanced Glycation End Products (AGEs) are modifiable by diet and reflect changes in healthy state. SALIVAGES investigates whether that diet-induced AGEs can act as reliable biomarkers of changes in health status and/or risk, focusing on the most highly accessible source of AGEs, the saliva. The main objectives of SALIVAGES were the…