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- Mitochondria represent central regulators of nutritional homeostasis and of the aging process. Epidemiological studies, including data from our cohort, indicate nutritional risk and preventive factors associated with dietary intake for the development of age-related parameters. Notably, studies from this network revealed the importance of a finely tuned mitochondria-autophagy axis as a preventive…
- BackgroundBacteria play a crucial role in our healthy development, and in protecting against chronic disease. The goal of EarlyVir was to find out whether the same applies for viruses and if we can isolate important viruses and use them as a technology to improve human health.Objectives:Determine the viral composition of the infant gut at age 1 yearDetermine whether it was influenced by the diet…
- The main objectives of the OCTOPUS project were:to determine, in mouse models, to what extent apoA-I/HDL modulate gut microbiota composition, intestinal homeostasis/immunity, plasma metabolome and atherosclerosis development.to determine whether apoA-I/HDL levels modulate gut microbiota composition and plasma metabolome in human cohorts, and to identify possible correlations between microbiota…
- Palatable, nutritious and digestible foods for prevention of undernutrition in active aging Image AbstractUndernutrition among older adults is a multifaceted challenge where the palatability, availability and cost of food intersect with metabolic effects and health outcomes. The research partners representing six…
