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- Metabolic disorders such as obesity and type 2 diabetes (T2D) represent a growing unmet clinical need. Accumulating evidence shows that the collection of microbes residing within the human intestinal tract influence host metabolism. Diet is one of the most important factors shaping the gut microbiome. So far, mainly microbial metabolism of dietary fibers has been studied, with less emphasis on…
- Coronary atherosclerosis is a leading cause of mortality and disability worldwide. Continuous efforts are needed to improve secondary prevention and understand the mechanism underlying disease progression. Based on primary prevention trials, a potential benefit of the Mediterranean diet after an acute coronary syndrome can be anticipated. The integrated microbiome-mediated/immunologic and…
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The overall goal of FOODPathS is to design the selforganizing prototype of the‘Partnership for Safe and Sustainable Food Systems (SSFS) for people, planet, and climate’ by following a systems approach and catalysing a change in mind-sets. - Image
In 2013 started the first Joint Funding Action (JFA) initiated by HDHL followed by six further funding activities until 2015. From these seven calls much can be learned for future activities. For this purpose, detailed evaluation reports were conducted to assess the monitoring data of the funded research projects in relation to the respective aim of the call and to analyse the output, outcomes and… - Image
ERA-HDHL was the first ERA-NET Cofund of HDHL and launched its first co-funded call in 2016: Biomarkers for Nutrition and Health (BioNH). In January 2022, ERA-HDHL ended and many interesting results were published, including from the co-funded call BioNH in which 13 countries and the European Commission (EC) funded a total of 12 research projects. - The Implementation Plan translates the objectives of the Strategic Research Agenda into tangible targets for the next three years and defines concrete funding and non-funding activities that will be carried out by the HDHL in the coming years.
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HDHL welcomes EPHA as new member of the Stakeholder Advisory Board (SHAB)! - The aim of Meatic project is to understand the role of the gut microbiome as determinant of the effect of diet on colorectal cancer risk and to identify specific associated microbiome profiles. We compared in humans (WP1) and experimental animals (WP2-WP3-WP4), a high-risk meat-based diet (MBD) with a pesco-vegetarian diet (PVD) associated with a lower CRC risk and a MBD diet medium risk…
- Early life is fundamental for brain and microbiota development. Gut microbiota influences brain function. Maternal obesity affects maturation of gut microbiota and is an important predictor of cognitive dysfunction in the offspring. Cognitive decline through life is an increasingly invalidating condition, due to population ageing and the high frequency of predisposing factors (obesity, unhealthy…
- Determinants of Diet and Physical Activity Knowledge Hub In 2012, the JPI HDHL launched its first Joint Action: Knowledge Hub on Determinants of Diet and Physical Activity Knowledge Hub (DEDIPAC KH). DEDIPAC started in 2014 and finished in 2016.
- European Nutritional Phenotype Assessment and Data Sharing Initiative In 2014, the JPI HDHL launched a call to establish a European Nutritional Phenotype Assessment and Data Sharing Initiative (ENPADASI). ENPADASI started in December 2014 and ended in summer 2017.