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101 results found for 'Diet, health and disease'.

  • CABALA_Diet & Health

    Duration:
    06/2017
    -
    05/2021
    Background and aimBile acids (BA) through G protein-coupled bile acid receptor 1 (GPBAR1 or TGR5) and nuclear receptors like Farnesoid X receptor (FXR) regulate mammalian inflammation, and lipid, glucose, energy, and xenobiotic metabolism. The gut microbiota modulates the enterohepatic circulation of BA and microbially produced secondary BA appear to be more potent receptor agonists than primary…

  • Project results: Early diet, infant gut immunity, and disease risk

    Nieuws
    9 May 2023
    Maternal and infant diets have long-term health effects, including obesity, allergies, and metabolic disorders. However, the exact molecular and cellular mechanisms through which dietary metabolites and contaminants impact health remain unclear.

  • Outcomes HDHL-INTIMIC 2017 call on Microbiome, Diet and Health

    Nieuws
    26 April 2023
    HDHL-INTIMIC was the second ERA-NET Cofund of JPI HDHL and launched its first call in 2017: Interrelation of the Intestinal Microbiome, Diet and Health. The call was funded by the EC and 8 countries. Supporting 11 research projects, the initiative concluded in December 2022, yielding significant new insights into how nutrition impacts health.

  • Project results: Understanding gut microbiota to reduce cardiometabolic disease

    Nieuws
    23 May 2023
    The gut microbiome is vital for health; low diversity increases non-communicable disease risk. While diet modulates this, effects are highly individual. Understanding these diet-microbiota interactions is essential for personalized nutrition and reducing cardiometabolic disease risk.

  • Karsten Köhler

    Page
    1 November 2023
    Research Area: Diet, Health and Disease

  • John Mathers

    Page
    1 November 2023
    Research Area: Diet, Health and Disease

  • Ellen Blaak

    Page
    1 November 2023
    Research Area: Diet, Health and Disease

  • Project results: The impact of Mediterranean diet on coronary atherosclerosis

    Nieuws
    6 June 2023
    Coronary atherosclerosis is a leading global cause of death. While the Mediterranean diet likely benefits patients after Acute Coronary Syndrome (ACS), the underlying microbiome, immune, and metabolic pathways remain unknown. Understanding these mechanisms is vital for improving secondary prevention and disease management.

  • Knowledge Platform on Food, Diet, Intestinal Microbiomics and Human Health (HDHL-INTIMIC 2018)

    Subsidie
    3 September 2018
    HDHL-INTIMIC launched the Knowledge Platform call in September 2018. The Knowledge Platform was funded in spring 2019 and started the same year.

  • Working Groups on Diet-related Diseases (2017)

    Subsidie
    22 May 2017
    In 2017 JPI HDHL launched a rapid action call to support a community-led working group that can push forward the field of diet-related chronic diseases. The working group that has been funded started in 2018 for one year.

  • Vacancy for Chair of Healthy Diet, Healthy Life

    Page
    31 May 2024
    The ‘Healthy Diet, Healthy Life’ (HDHL) initiative is looking for candidates for the position of Chair of the Management Board.

  • Project results: Bile acids, fiber, and non-alcoholic fatty liver disease

    Nieuws
    7 April 2023
    NAFLD affects 25-30% globally, yet lacks specific treatment. Research now targets the liver–gut axis and bile acids. Soluble fibers, like oat β-glucans, may improve liver health by binding bile acids and altering the gut microbiota to improve metabolic parameters.