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results found for 'Diet, health and disease'.
- Coronary atherosclerosis is a leading cause of mortality and disability worldwide. Continuous efforts are needed to improve secondary prevention and understand the mechanism underlying disease progression. Based on primary prevention trials, a potential benefit of the Mediterranean diet after an acute coronary syndrome can be anticipated. The integrated microbiome-mediated/immunologic and…
- Dietary Patterns in the Ageing European Population: an Interdisciplinary Approach to combat Overweight-Related Metabolic Diseases. The EURODIET project Image AbstractAn epidemic of overweight/obesity, metabolic syndrome and cardio-metabolic diseases is emerging at planetary level, and healthy nutrition represents a critical help to…
- Prevention in prediabetic patients of infection’s morbidity following a high fiber and vegetal protein diet Image Abstract Obesity is a global health concern with rising proportion of existing cases, and it is associated with numerous comorbidities, including an increased risk of infections and a more severe…
- Combining biomarker panels and dietary intake data for improved assessment of healthful/unhealthful plant food intake Image AbstractAccurate information on food intake is necessary to investigate diet-health associations. Traditional assessment methods depend on self-reported data, which are prone to measurement…
- Background and aimThe aryl hydrocarbon receptor (AhR) is a transcription factor recently shown to be crucial for the maintenance of intestinal homeostasis, however its precise gut luminal activators and functional consequences are unknown. Activators originate from (i) the diet, such as indole-3-carbinol from cruciferous vegetables, (ii) the microbiota, (iii) lactic acid bacteria, used in food or…
- Main objectives/results:SA1- identification of effector proteinsEffector analysis and selection from genome sequenced reference strains:Identification of 77 genome sequenced reference strains for proteobacterial strains isolated from the human gut Application of Machine Learning tools for deeper T3SS screening -> 44 strains with 3000 effectors identified/selectedFunctional (relation to diet…
- Background and aim:Studies suggest that the intestinal microbiome modulates the risk of several chronic diseases, including type 2 diabetes, allergy, cardiovascular disease, and colorectal cancer (CRC). Dietary factors are related to chronic disease risk, and they have been suggested to modulate the composition and function of the gut microbiome. However, detailed knowledge on the relationship of…
- Background and aimAccording to the Developmental Origins of Health and Disease hypothesis early life exposure to environmental factors plays a critical role in defining offspring health in childhood and later life. Thus adaptation to suboptimal nutrition during pregnancy or early childhood may perpetuate intergenerational transmission of a range of adverse health outcomes. Epigenetic phenomena…
- The human gut microbiota has been linked with incidence and progression of noncommunicable diseases and their riskfactors. Moreover, diet has been identified as an important modulator of microbiota composition and function, but responsesvary across individuals.DiGuMet aimed to explore how gut microbiota interacts with diet and the role of such interactions for cardiometabolic diseaserisk and to…
- From diet to a healthy immune system: understanding biological food paths to oppose metabolic syndromes and infectious diseases