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results found for 'Diet, health and disease'.
- The project aimed at evaluating the specific role of selenium (Se) in relation to other nutrients and trace elements in favoring brain and behavioral plasticity. The central hypothesis tested is the role of oxidative stress and inflammation as key processes connecting diet, peripheral tissues and brain development. In our experimental models, pregnant and lactating female rats and their offspring…
- Low or imbalanced dietary and biomarker status of folate and interrelated B-vitamins (methyl donor nutrients) perturb 1-carbon metabolism, and adversely affect brain development in early life and brain function in later life. The biological mechanisms explaining these relationships are not clear but may involve DNA methylation of epigenetically-controlled genes related to brain development and…
- Genetic carbohydrate maldigestion as a model to study food hypersensitivity mechanism and guide personalised treatment using a non-invasive multi-parametric test Image AbstractIt is estimated that about 20% of the population has a food intolerance and that in people with Irritable Bowel Syndrome which affects about 1 in…
- Carbohydrate staple foods - facing the challenge to improve their quality for a better metabolic healthAbstract Image Carbohydrates are the main energy source in most European diets. Their metabolic effects depend on several aspects ranging from chemical structure to food matrix and food processing which are best captured by the…
- Background and aimSub-optimal status of Riboflavin (vitamin-B2) may be more widespread than generally recognised because of reliance on dietary data only in many nutrition surveys and lack of reliable biomarker data. The DERiVE project aimed to address this by developing accessible riboflavin biomarkers and by demonstrating important functional, gene-nutrient and health effects of optimal…