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Six proposals are selected for funding under the recent NUTRIMMUNE call, receiving a total of € 5,9 million of funding. The projects to be funded by this call will help to better understand the interactions between nutrition and immunity within the context of its interplay between infectious diseases and diet-related metabolic diseases. - Image
Today is World Diabetes Day, highlighting the urgent need to tackle this global health crisis. The International Diabetes Federation, WHO, and UN are leading a global campaign focused on this year's theme: "Access to Diabetes Care." This day underscores the importance of ensuring treatment and support are available to millions worldwide. - Obesity promotes Non Alcoholic Fatty Liver Diseases (NAFLD) through mechanisms involving the gut microbiota. From 2 cohorts of obese women (FLORINASH FP7), in which a multilevel omics approach was used, we identified a microbiome architecture indicating increased dietary lipids processing. This was associated with hepatic insulin signaling perturbations, a transcriptomic profile indicative of…
- Man is colonized immediately upon birth by environmental microbes of primarily maternal origin. Initial colonization and transfer of maternal immunity through breastfeeding are believed to impact infant health at short- and long-term by conferring protection from infection and potentially resistance to metabolic and allergic diseases. Our objectives are to assess the importance of dietary habits…
- Genetic predisposition and general overnutrition are discussed as key factors in the development of non-alcoholic fatty liver disease (NAFLD); however, alterations of intestinal microbiota composition and associated impairments of intestinal barrier function are thought to be critical in the onset and progression of NAFLD. Also studies suggest a pivotal role of bile acids and microbial bile acid…
- Main objectives/results:SA1- identification of effector proteinsEffector analysis and selection from genome sequenced reference strains:Identification of 77 genome sequenced reference strains for proteobacterial strains isolated from the human gut Application of Machine Learning tools for deeper T3SS screening -> 44 strains with 3000 effectors identified/selectedFunctional (relation to diet…
- The human gut microbiota has been linked with incidence and progression of noncommunicable diseases and their riskfactors. Moreover, diet has been identified as an important modulator of microbiota composition and function, but responsesvary across individuals.DiGuMet aimed to explore how gut microbiota interacts with diet and the role of such interactions for cardiometabolic diseaserisk and to…
- PREcisE’s goal is to use longitudinal data from the pre-conceptional period up until adulthood to explore the life-course and molecular pathways pertaining the mother to offspring transmissibility of impaired glycaemic health. The project harnesses very large data from cohorts/biobanks from Spain, Germany, Finland, France and the Netherlands. It also joins hands with related projects (e.g…
- Nutrition and Cognitive Function In 2015, the JPI HDHL launched the Joint Action: Nutrition and Cognitive Function (NutriCog). The five funded projects started in the first half of 2016 for a period of 3 years.
- In 2015 the JPI HDHL launched the Joint Action: Intestinal Microbiomics. The Joint Action funded 6 projects that started early 2016 for 3 to 3,5 years.
- Food Processing for Health In 2015 the JPI HDHL launched the Joint Action: Food Processing for Health. The funded projects LONGLIFE and ProHealth ran for 3 years from March 2016 to March 2019.
- Biomarkers for Nutrition and Health (co-funded call) In February 2016, 14 countries launched the first ERA-HDHL Cofunded joint call for funding multilateral research projects on “Biomarkers for nutrition and health”. This Joint Action funded 12 projects that started in the beginning of 2017 for about 3 years.