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- Dietary Patterns in the Ageing European Population: an Interdisciplinary Approach to combat Overweight-Related Metabolic Diseases. The EURODIET project Image AbstractAn epidemic of overweight/obesity, metabolic syndrome and cardio-metabolic diseases is emerging at planetary level, and healthy nutrition represents a critical help to…
- Obesity promotes Non Alcoholic Fatty Liver Diseases (NAFLD) through mechanisms involving the gut microbiota. From 2 cohorts of obese women (FLORINASH FP7), in which a multilevel omics approach was used, we identified a microbiome architecture indicating increased dietary lipids processing. This was associated with hepatic insulin signaling perturbations, a transcriptomic profile indicative of…
- The physiological impact of dietary methylglyoxal Image AbstractBioactive compounds produced during food processing can have strong pro-inflammatory properties with potential health implications. Modulation of chronic inflammation may be the mechanism linking diet to the risk of chronic diseases such as diabetes and cardiovascular…
- Sulfur amino acids, energy metabolism and obesity Image AbstractResearch over the last decade suggests that methionine and cysteine, two dietary sulfur amino acids that are abundant in proteins from animal sources, play a role in development of obesity and related metabolic diseases. In rodents, experiments with diets low in…
- Preventing obesity, sarcopenia, and Sarcopenic Obesity in retirement – digital personalized interventions for healthy NUTrition and physical activity for Seniors Image AbstractThe aging population faces two conditions that threaten healthy aging: high fat mass (obesity) and low muscle mass and function (sarcopenia). The…
- Carbohydrate staple foods - facing the challenge to improve their quality for a better metabolic healthAbstract Image Carbohydrates are the main energy source in most European diets. Their metabolic effects depend on several aspects ranging from chemical structure to food matrix and food processing which are best captured by the…
- Innovative plant protein fibre and physical activity solutions to address poor appetite and prevent undernutrition in older adults Image AbstractOlder adults with poor appetite are at high risk of undernutrition due to the role of appetite as key driver of food intake. Although a negative impact on health is known, there…
