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- Sulfur amino acids, energy metabolism and obesity Image AbstractResearch over the last decade suggests that methionine and cysteine, two dietary sulfur amino acids that are abundant in proteins from animal sources, play a role in development of obesity and related metabolic diseases. In rodents, experiments with diets low in…
- BackgroundChildhood obesity is a rapidly growing problem in many countries across the world. Weight loss programs have limited effects and prevention is our only hope to stem this new epidemic. Development in the early life period has lifelong consequences. Early visceral fat mass development, in particular, is thought to have long-term effects on later body fat mass and fat distribution, and thus…
- Metabolic disorders such as obesity and type 2 diabetes (T2D) represent a growing unmet clinical need. Accumulating evidence shows that the collection of microbes residing within the human intestinal tract influence host metabolism. Diet is one of the most important factors shaping the gut microbiome. So far, mainly microbial metabolism of dietary fibers has been studied, with less emphasis on…
- Background and aimFAME aimed to a) identify novel lipidomics biomarkers as biomarkers of fatty acid status and of future cardiometabolic clinical events, b) establish relationships between diet and tissue status of fatty acids as explanatory factors for diet relationships with cardiometabolic health, and c) to investigate genetic determinants of fatty acid status and metabolism which modify the…
- Food phytochemicals matter for cardiometabolic health Image AbstractFOODPHYT aims at raising awareness and understanding of the enormous potential of food phytochemicals to support the global fight against obesity and associated cardiometabolic diseases. Phytochemicals are small molecules synthetized by plants for their protection…
- Cumulative evidence suggests that food allergy (FA) is associated with a multitude of environmental factors including hygiene habits, antibiotic use, lifestyle changes and, in particular, diet. Changes in nutrition can result in dysbiosis of the skin, gut, and lung microbiota and generate changes in microbial the metabolites produced, which may in turn produce epigenetic modifications. Current…
- Low or imbalanced dietary and biomarker status of folate and interrelated B-vitamins (methyl donor nutrients) perturb 1-carbon metabolism, and adversely affect brain development in early life and brain function in later life. The biological mechanisms explaining these relationships are not clear but may involve DNA methylation of epigenetically-controlled genes related to brain development and…
