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results found for 'Diet, health and disease'.
- Food phytochemicals matter for cardiometabolic health Image AbstractFOODPHYT aims at raising awareness and understanding of the enormous potential of food phytochemicals to support the global fight against obesity and associated cardiometabolic diseases. Phytochemicals are small molecules synthetized by plants for their protection…
- The main objectives of the OCTOPUS project were:to determine, in mouse models, to what extent apoA-I/HDL modulate gut microbiota composition, intestinal homeostasis/immunity, plasma metabolome and atherosclerosis development.to determine whether apoA-I/HDL levels modulate gut microbiota composition and plasma metabolome in human cohorts, and to identify possible correlations between microbiota…
- Increasing evidence suggests that several non-communicable diseases, including obesity and its associated metabolic disorders, are inherited from parents to offspring over several generations by non-genetic mechanisms.In this context, it has been suggested that parental environmental cues might induce epigenetic modifications in the germ line, which are transmitted to the progeny. Hence…
- Nutrition and aryl hydrocarbon receptoractivation in mesenteric adipose tissueinflammation and intestinal surgical site Image AbstractObesity and sedentary lifestyles are facing society with an increasing burden of affiliated health problems such as metabolic syndrome, cardiovascular disease, and type 2 diabetes…
- Microbial colonization of the new-born is essential for the development of the physiological homeostasis of the host. Perturbations of early-life colonization may have long-lasting effects on host health; specific alterations seem to precede the development of disease, including both communicable and non-communicable diseases. Thus, early microbiota establishment has a profound effect on long-term…
- Man is colonized immediately upon birth by environmental microbes of primarily maternal origin. Initial colonization and transfer of maternal immunity through breastfeeding are believed to impact infant health at short- and long-term by conferring protection from infection and potentially resistance to metabolic and allergic diseases. Our objectives are to assess the importance of dietary habits…
- Physiological and Ecological impact of pre- and probiotic interventions in relation to food allergy in early-lifeAbstract Image The co-evolution of man and microbiota has diversified the nutrients compatible with human digestion and thus survival. The increased fitness obtained from a better access to food has favored…
- Preventing peanut allergy through improved understanding of the transcutaneous sensitisation route, novel food processing and skin care adaptations Image AbstractAllergic diseases, including atopic dermatitis (AD, also called ‘atopic eczema’) and food allergies (FA), affect over a quarter of all children across Europe…
- Background and aimThe Joint Programming Initiative on a Healthy Diet for a Healthy Life (JPI HDHL), involved 28 research institutes from seven European countries and New Zealand combined their expertise to form the Policy Evaluation Network (PEN). PEN, true to its vision, has improved knowledge, tools and capacity among its network and beyond to identify, evaluate and benchmark policies designed…
- PREcisE’s goal is to use longitudinal data from the pre-conceptional period up until adulthood to explore the life-course and molecular pathways pertaining the mother to offspring transmissibility of impaired glycaemic health. The project harnesses very large data from cohorts/biobanks from Spain, Germany, Finland, France and the Netherlands. It also joins hands with related projects (e.g…