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- Genetic predisposition and general overnutrition are discussed as key factors in the development of non-alcoholic fatty liver disease (NAFLD); however, alterations of intestinal microbiota composition and associated impairments of intestinal barrier function are thought to be critical in the onset and progression of NAFLD. Also studies suggest a pivotal role of bile acids and microbial bile acid…
- Biomarker signatures of diet, physical activity and sleep in children and youth Image AbstractBackground & Aims:Diet and physical activity are lifestyle factors that may affect differently to subjects depending on their genetics and environment. Metabolomics and Proteomics are…
- First 1000 days Strategies to Prevent Childhood Obesity Image AbstractChildhood obesity is a major public health problem leading to short-term and long-term adverse health outcomes, reduced quality of life and high societal costs. Obesity and…
- Important gaps remain in our understanding how diet and the composition of the gut microbiota influence the function of our immune system. TransMic focused on communities in sub-Saharan Africa that are in different stages of urbanization and a nutrition and epidemiologic transition. These communities offer unique opportunities to investigate the ‘diet-microbiome-health’ axis for the following…
