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- Biomarker signatures of diet, physical activity and sleep in children and youth Image AbstractBackground & Aims:Diet and physical activity are lifestyle factors that may affect differently to subjects depending on their genetics and environment. Metabolomics and Proteomics are…
- BackgroundChildhood obesity is a rapidly growing problem in many countries across the world. Weight loss programs have limited effects and prevention is our only hope to stem this new epidemic. Development in the early life period has lifelong consequences. Early visceral fat mass development, in particular, is thought to have long-term effects on later body fat mass and fat distribution, and thus…
- Early life is fundamental for brain and microbiota development. Gut microbiota influences brain function. Maternal obesity affects maturation of gut microbiota and is an important predictor of cognitive dysfunction in the offspring. Cognitive decline through life is an increasingly invalidating condition, due to population ageing and the high frequency of predisposing factors (obesity, unhealthy…
- Background and aimHEALTHMARK investigated the complex associations between diet, microbiota, tryptophan metabolites of microbial metabolism, and metabolic health in a set-up of identification, replication, and validation of associations. The project, organized in five work packages (WP) comprised two observational and two intervention studies.In WP1, the University of Bonn (UB) using the DOrtmund…
- A comprehensive study of the innate immune surveillance against infection during postprandial metabolism Image AbstractPostprandial inflammation describes a systemic state of activation of immune cells following the ingestion of macronutrients from food. While this response helps fight infections, it…
