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- Background and aim There is an urgent need to find reliable early biomarkers of the cardiometabolic syndrome (CardMetS) allowing intervention before irreversible damage develops while assessing the efficacy of nutritional prevention. Oxylipins could be relevant candidate biomarkers thanks to their involvement in the homeostatic regulation of various process related to the cardiometabolic status…
- Determinants of Diet and Physical Activity; Knowledge Hub to integrate and develop infrastructure for research across Europe: From December 2013 until December 2016 the research network ‘DEDIPAC’ was active. DEDIPAC stands for ‘DEterminants of DIet and Physical ACtivity’. The main goal of DEDIPAC was to establish a research network (Knowledge Hub) of researchers from different countries and…
- Background and aimThe FiberTAG project has established a set of biomarkers linking dietary fiber (DF) intake and gut microbiota-related health effect. We aim at refining the concept of DF based on novel biological effects that can occur upon gut microbiota-nutrients interaction by using existing cohorts and by developing innovative approaches to evaluate the health interest of novel insoluble DF…
- Low or imbalanced dietary and biomarker status of folate and interrelated B-vitamins (methyl donor nutrients) perturb 1-carbon metabolism, and adversely affect brain development in early life and brain function in later life. The biological mechanisms explaining these relationships are not clear but may involve DNA methylation of epigenetically-controlled genes related to brain development and…
- Background and aimThe SALAMANDER project aimed at defining salivary signatures indicative of healthy dietary choices (adherence to a Mediterranean diet: MeDi) with a positive long-term health outcome (protection against type 2 diabetes: T2DM).In a discovery phase, 214 subjects were selected in two cohorts of elderly people (3-C Bordeaux in France, Seniors-ENRICA in Spain) following a case-control…
- PREcisE’s goal is to use longitudinal data from the pre-conceptional period up until adulthood to explore the life-course and molecular pathways pertaining the mother to offspring transmissibility of impaired glycaemic health. The project harnesses very large data from cohorts/biobanks from Spain, Germany, Finland, France and the Netherlands. It also joins hands with related projects (e.g…
