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results found for 'Biomarkers'.
- Man is colonized immediately upon birth by environmental microbes of primarily maternal origin. Initial colonization and transfer of maternal immunity through breastfeeding are believed to impact infant health at short- and long-term by conferring protection from infection and potentially resistance to metabolic and allergic diseases. Our objectives are to assess the importance of dietary habits…
- Carbohydrate staple foods - facing the challenge to improve their quality for a better metabolic healthAbstract Image Carbohydrates are the main energy source in most European diets. Their metabolic effects depend on several aspects ranging from chemical structure to food matrix and food processing which are best captured by the…
- The main objectives of the OCTOPUS project were:to determine, in mouse models, to what extent apoA-I/HDL modulate gut microbiota composition, intestinal homeostasis/immunity, plasma metabolome and atherosclerosis development.to determine whether apoA-I/HDL levels modulate gut microbiota composition and plasma metabolome in human cohorts, and to identify possible correlations between microbiota…
- Tailored Carbohydrate Quality for Personalized Weight Management and Metabolic Health Image AbstractThis project investigates the role of carbohydrate quality (CQ) on weight management, appetite and cardiometabolic health in humans as well as underlying mechanisms by which CQ affects consumers. It will also promote career…
- Cardiovascular and metabolic diseases are a primary cause of morbidity and mortality worldwide. Diet is a major risk factor for cardio-metabolic health, but is challenging to study in part because metabolic response to diet is highly individualised. Characterising the molecular pathways that mediate personalised responses to diet is critical to effectively tackle the current epidemic. Epigenetic…
- Background and aimAccording to the Developmental Origins of Health and Disease hypothesis early life exposure to environmental factors plays a critical role in defining offspring health in childhood and later life. Thus adaptation to suboptimal nutrition during pregnancy or early childhood may perpetuate intergenerational transmission of a range of adverse health outcomes. Epigenetic phenomena…
- Microbial colonization of the new-born is essential for the development of the physiological homeostasis of the host. Perturbations of early-life colonization may have long-lasting effects on host health; specific alterations seem to precede the development of disease, including both communicable and non-communicable diseases. Thus, early microbiota establishment has a profound effect on long-term…